Research: All Articles
Former FBI Director Discusses the Dangers of Allowing Drug Importation in Radio Interview
Freeh warned that allowing drug importation from Canada was akin to allowing drugs to be imported from anywhere. Quality would be at risk, and the opioid crisis, an epidemic that killed over 33,000 Americans in 2015, would only get worse. He said that allowing drug importation, “…will not only fuel that, but it will also, in my opinion, encourage a lot of criminal groups and organizations that heretofore have not been involved in this trade, but will see huge opportunities to enter the market.”
[...]Nayyar, Gaurvika M. L. et al., “The Global Pandemic of Falsified Medicines: Laboratory and Field Innovations and Policy Perspectives,” The American Journal of Tropical Medicine and Hygiene, Volume 92, Issue 6_Suppl, Jun 2015, p. 2 – 7
Introduction This supplement to the American Journal of Tropical Medicine and Hygiene, entitled “The pandemic of falsified medicines: laboratory and field innovations and policy perspectives,” showcases 17 articles on detection technologies and methods, field surveillance data, multisectorial perspectives, and policy interventions and recommendations needed to create a coordinated and effective response to curb the pandemic…
[...]Weaver, Abigail A., et al. “Paper Analytical Devices for Fast Field Screening of Beta Lactam Antibiotics and Antituberculosis Pharmaceuticals.” Analytical Chemistry 85, no. 13
Abstract: Reports of low-quality pharmaceuticals have been on the rise in the past decade, with the greatest prevalence of substandard medicines in developing countries, where lapses in manufacturing quality control or breaches in the supply chain allow substandard medicines to reach the marketplace. Here, we describe inexpensive test cards for fast field screening of pharmaceutical…
[...]Traynor, Kate. “California pharmacy board takes next steps toward electronic pedigree.” American Journal Of Health-System Pharmacy 70, no. 4 (February 15, 2013): 303-304.
The article reports that the California State Board of Pharmacy held a meeting in December 2012 to address comments from the public regarding requirements for electronic record of transactions for prescription drugs. Traynor, Kate. "California pharmacy board takes next steps toward electronic pedigree." American Journal Of Health-System Pharmacy 70, no. 4 (February 15, 2013):…
[...]Ortiz, R, de Cássia Mariotti, K, Fank, B, Limberger, R, Anzanello, M, & Mayorga, P 2013, ‘Counterfeit Cialis and Viagra fingerprinting by ATR-FTIR spectroscopy with chemometry: Can the same pharmaceutical powder mixture be used to falsify two medicines?’
Abstract This paper proposes a direct and efficient method to discriminate between counterfeit and authentic Cialis and Viagra samples by combining attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy with multivariate techniques. The chemical profile of 53 commercial samples (Viagra®, Cialis®) and 104 counterfeit samples (Viagra and Cialis) from distinct seizures were obtained from ATR-FTIR…
[...]Lu, Feng, et al. “A novel identification system for counterfeit drugs based on portable Raman spectroscopy.” Chemometrics & Intelligent Laboratory Systems 127, (August 15, 2013): 63-69.
Highlights A novel identification system for screening of the counterfeit drugs is proposed. The strategy provides an alternative. The strategy is demonstrated with high rapidity, accuracy and cost-effectiveness. AbstractQuick inspection methods for counterfeit drugs are of vital necessity. In this study, the feasibility of portable Raman spectroscopy as an analytical method together with a…
[...]Lebel, Philippe, et al. “A rapid, quantitative liquid chromatography-mass spectrometry screening method for 71 active and 11 natural erectile dysfunction ingredients present in potentially adulterated or counterfeit products.” Journal Of Chromatography A
Highlights The reported LC-MS/MS method resolved 82 erectile dysfunction (ED) drugs in 10 min. ED drug extraction from different matrices gave recoveries from 92 to111%. The screening method was successfully applied to more than 32 samples. The method is faster and more sensitive than currently used and reported methods. Identification of additional species, in an…
[...]Custers, D., et al. “Headspace–gas chromatographic fingerprints to discriminate and classify counterfeit medicines.” Talanta 123, (June 2014): 78-88.
Highlights Fingerprints might contribute to the health risk evaluation of counterfeit drugs. GC-fingerprints were used to discriminate between genuine and counterfeit medicines. Fingerprints were analyzed using different chemometric techniques. Principal Component Analysis clearly discriminated between genuine and counterfeit. Soft Independent Modelling of Class Analogy generated the best predictive models. Abstract Counterfeit medicines are a global…
[...]Bunaciu, Andrei A., Şerban Fleschin, and Hassan Y. Aboul-Enein. “Spectroscopic Analytical Methods for Detection of Counterfeit Pharmaceutical Preparations — A Mini-Review.” Gazi University Journal Of Science 26, no. 3 (July 2013): 407-417
Abstract Pharmaceutical counterfeiting is becoming a serious problem all over the world. This paper presents several of the most important methods used to elucidate this problem including near- and mid-infrared spectroscopy, Raman spectroscopy, isotopic characterization, chromatographic and mass spectrometric approaches. Bunaciu, Andrei A., Şerban Fleschin, and Hassan Y. Aboul-Enein. "Spectroscopic Analytical Methods for Detection of…
[...]Broad, N. W., C. Dentinger, and J. Pasmore. “Advantages of 1064-nm Portable Raman for Counterfeit Pharmaceuticals Authentication.” Spectroscopy (June 2, 2013): 22-31
The counterfeiting of pharmaceuticals is a global issue that is expanding each year. The severity of drugs counterfeited has increased from lifestyle drugs to include lifesaving (such as anticancer) types in recent times. The miniaturization of instrumentation has led to out-of-laboratory analysis for product authentication. Raman spectroscopy is ideal for pharmaceutical identifications and has been…
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